Discovery of 7-N-piperazinylthiazolo [5, 4-d] pyrimidine analogues as a novel class of immunosuppressive agents with in vivo biological activity

MY Jang, Y Lin, S De Jonghe, LJ Gao…

文献索引：Journal of Medicinal Chemistry, , vol. 54, # 2 p. 655 - 668

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被引用次数: 27

摘要

... Journal of Medicinal ... neurotoxicity, hyperlipidaemia, new-onset post-transplant diabetes mellitus, and hypertension.(2) Thus, a high medical need exists ... pyrimidine scaffold is not very frequently used in drug discovery programs, as the number of medicinal chemistry projects that ...