Synthetic communications

One-pot Mitsunobu-Staudinger preparation of 3-aminocholan-24-oic acid esters from 3-hydroxycholan-24-oic acid esters

PL Anelli, L Lattuada, F Uggeri

文献索引：Anelli, Pier Lucio; Lattuada, Luciano; Uggeri, Fulvio Synthetic Communications, 1998 , vol. 28, # 1 p. 109 - 117

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被引用次数: 39

摘要

Abstract 3-Hydroxycliolnn-23-oi~ acid esters are easily converted mto the correspoiiduig 3-aniiiio derivatives zuil Mitsuiwbu reaction with d~phe~~ylpl~os~~lioryl azde (DPPA) and Stntidinger reduction w ~ th PPhg/H20 of tlir intermediate azrdo cornpound 111 THF ... Gadolinium complexes are roiitinely used in niedicuie as contrast agents for ... Magnetic Resonance Imaging (MRI) but there is still inuch attention to the ... In particular, 3-niiiinoiliolan-24-nic acid esters are ...