Formation of mono-and diglucuronides and other glycosides of benzo (a) pyrene-3, 6-quinol by V79 cell-expressed human phenol UDP-glucuronosyltransferases of …
H Gschaidmeier, A Seidel, B Burchell…
文献索引：Gschaidmeier, Harald; Seidel, Albrecht; Burchell, Brian; Bock, Karl Walter Biochemical Pharmacology, 1995 , vol. 49, # 11 p. 1601 - 1606
Glucuronidation of quinols of polycyclic aromatic hydrocarbons (PAHs) represents an important detoxication pathway preventing toxic quinone/quinol redox cycles. Therefore, mono-and diglucuronide formation of benzo (a) pyrene-3, 6-quinol was investigated and compared to that of structurally related 3, 6-dihydroxychrysene and simple phenols (1- naphthol and 4-methylumbelliferone) using V79 cell-expressed human UGT1. 6 (= P1) ...
