Synthesis and properties of N2, 3-ethenoguanosine and N2, 3-ethenoguanosine 5'-diphosphate

JT Kusmierek, DE Jensen, SJ Spengler…

文献索引：Kusmierek, Jaroslaw T.; Jensen, David E.; Spengler, Sylvia J.; Stolarski, Ryszard; Singer, B. Journal of Organic Chemistry, 1987 , vol. 52, # 12 p. 2374 - 2378

全文：HTML全文

被引用次数: 31

摘要

w, 3-Ethenoguanosine has not been reported as a product of guanosine reaction with haloacetaldehydes. This is in contrast to the reaction of the ribosides yielding the well- known etheno compounds l, N% Ado, 3, iV4-&yd, and 1, IP-tGuo. The base,@, 3- ethenoguanine was, however, synthesized, but not by direct reaction. We now report the synthesis of the nucleoside via reaction of 06-benzylguanosine with bromoacetaldehyde ...