Journal of Heterocyclic Chemistry

Synthesis and reactions of 3??carbethoxy and 3??aroyl??3, 4??dihydro??1h??2, 3??benzoxazin??1??ones

A Trani, E Bellasio

文献索引：Trani,A.; Bellasio,E. Journal of Heterocyclic Chemistry, 1977 , vol. 14, p. 113 - 117

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被引用次数: 0

摘要

Abstract A series of 3-substituted 3, 4-dihydro-1H-2, 3-benzoxazin-1-ones (IV)(Scheme I) was prepared by reaction of 2-bromomethylbenzoyl chlorides (II) with N- hydroxyethylcarbamate (III) or with benzohydroxamic acids. Acid hydrolysis of 3-carbethoxy (IVa) and 3-benzoyl derivatives (IVb) afforded a mixture of 2-(hydroxyaminomethyl) benzoic acid (V) and 2, 3-dihydro-2-hydroxy-1H-1-isoindolinone (VII). Compound IVa reacted with ...