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The Journal of Organic Chemistry

Chiral synthesis of doxpicomine

E Farkas, CJ Sunman

文献索引:Farkas, Eugene; Sunman, Cheryl J. Journal of Organic Chemistry, 1985 , vol. 50, # 7 p. 1110 - 1112

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被引用次数: 27

摘要

The presence of amino groups and their likely com-plexation with borohydride may alter this interpretation. The diastereomeric product obtained was of sufficient optical purity to be used to complete the synthesis of the target amine 1. In addition, the desired pure R, S diastereomer was isolated at this point as either the free base or the monohydrochloride. The former was obtained optidy pure in 55% yield. Optically pure R, S hydrochloride was ...