1, 3-Dioxolane formation via Lewis acid-catalyzed reaction of ketones with oxiranes

DS Torok, JJ Figueroa, WJ Scott

文献索引：Torok, Daniel S.; Figueroa, John J.; Scott, William J. Journal of Organic Chemistry, 1993 , vol. 58, # 25 p. 7274 - 7276

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被引用次数: 59

摘要

1, 3-Dioxolanes are among the most widely used protecting groups for carbonyl compound^.^ The most common methods for the synthesis of these acetals employ protic acids, aqueous conditions, or high temperatures, making them unsuitable for the protection of sensitive compounds. A gentle, low temperature method for the formation of ethylene acetals might involve the acidcatalyzed addition of an epoxide to a ketone. Bogert and ...