First regioselective enzymatic acylation of amino groups applied to pyrimidine 3', 5'-diaminonucleoside derivatives. Improved synthesis of pyrimidine 3', 5'-diamino-2', …
I Lavandera, S Fernández, M Ferrero…
文献索引：Lavandera; Fernandez; Ferrero; Gotor Journal of Organic Chemistry, 2001 , vol. 66, # 11 p. 4079 - 4082
The chemistry of natural nucleosides and their analogues has been widely studied due to their potential as fungicidal, antitumor, and antiviral agents. 1 Consequently, extensive modifications have been made to both the heterocyclic base and the sugar moiety in order to avoid the drawbacks shown by nucleosides or analogues in certain applications.
