New syntheses of tetrazolylmethylphenylalanine and O-malonyltyrosine as pTyr mimetics for the design of STAT3 dimerization inhibitors

J Dourlat, B Valentin, WQ Liu, C Garbay

文献索引：Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 14 p. 3943 - 3946

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被引用次数: 25

摘要

... Bioorganic & Medicinal Chemistry Letters. ... Tpa, Pmp, and l-O-(carboxymethyl)phenylalanine, 14, 23 and 24 were also prepared and introduced in the Ac-pYLPQTV sequence ( Table 1). Peptide synthesis was performed on solid phase on HMP resin by Fmoc chemistry. 22. ...