Design and structure-activity relationships of potent and selective inhibitors of blood coagulation factor Xa

WR Ewing, MR Becker, VE Manetta…

文献索引：Journal of Medicinal Chemistry, , vol. 42, # 18 p. 3557 - 3571

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被引用次数: 40

摘要

... Journal of Medicinal Chemistry. ... Chemistry. The enantiomerically pure 3-amino lactam scaffolds (Table 1) were prepared from either direct methods or known literature procedures. 9 Both enantiomers of the 3-amino ...