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The Interaction of α-Chymotrypsin with a Series of α-N-Acetyl-α-amino Acid Methylamides1

TH Applewhite, C Niemann

文献索引:Applewhite; Niemann Journal of the American Chemical Society, 1959 , vol. 81, p. 2208,2213

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被引用次数: 34

摘要

The aN-acetyl-a-amino acid methylamides derived from glycine, L-alanine, L-isoleucine, L- methionine, L-proline, L-hydroxyproline, L-histidine, D-and L-phenylalanine, D-and L- tyrosine and D-and L-tryptophan have been examined with respect to their ability to inhibit the o-chymotrypsin catalyzed hydrolysis uf benzoyl-L-valine methyl ester. The cytent of interaction of the enzyme with the first seven compounds was insufficient to permit ...