IRAK-4 inhibitors. Part III: a series of imidazo [1, 2-a] pyridines

GM Buckley, R Fosbeary, JL Fraser, L Gowers…

文献索引：Bioorganic and Medicinal Chemistry Letters, , vol. 18, # 12 p. 3656 - 3660

被引用次数: 55

摘要

... Bioorganic & Medicinal Chemistry Letters. ... A variety of N-linked derivatives were prepared using an automated serial microwave reactor, 4 either by direct S N Ar chemistry (method b) or by using Buchwald palladium catalysed couplings (method c). 5 Bifunctional bis-amines ...

885275-59-2

6-氯-3-碘咪唑并[1,2-a]吡啶

IRAK-4 inhibitors. Part III: a series of imidazo [1, 2-a] py...

[Buckley, George M.; Fosbeary, Richard; Fraser, Joanne L.; Gowers, Lewis; Higueruelo, Alicia P.; James, Lynwen A.; Jenkins, Kerry; Mack, Stephen R.; Morgan, Trevor; Parry, David M.; Pitt, William R.; Rausch, Oliver; Richard, Marianna D.; Sabin, Verity Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 12 p. 3656 - 3660]