Synthesis of peptide analogs of the N-terminal eicosapeptide sequence of ribonuclease A. IX. Synthesis of [Serine6, Ornithine10]-and [Proline6, Ornithine10] …

F Marchiori, R Rocchi, L Moroder…

文献索引：Marchiori; Rocchi; Moroder; Fontana; Scoffone Journal of the American Chemical Society, 1968 , vol. 90, # 21 p. 5889 - 5894

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被引用次数: 8

摘要

Abstract: Syntheses are described of two analogs of the S-peptide in which the arginyl residue in position 10 is replaced by ornithine and the alanyl residue in position 6 by either serine or proline. The stereochemical homogeneity of these peptides, Le., lysylglutamylthreonylalanylalanylseryllysylp... and lysylglutamylthreonylalanylalanylprolyllysylp..., was assessed by digestion with aminopeptidase M followed by quantitative amino acid analysis. The enzymic properties ...