Chemische Berichte

Nucleoside syntheses, XXV1) A new simplified nucleoside synthesis

H Vorbrüggen, B Bennua

文献索引：Vorbrueggen, Helmut; Bennua, Baerbel Chemische Berichte, 1981 , vol. 114, # 4 p. 1279 - 1286

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被引用次数: 309

摘要

Abstract The several steps of the Friedel-Crafts catalyzed silyl-Hilbert-Johnson nucleoside synthesis-silylation of the heterocyclic base, silylation of the perfluorosulfonic acids or its salts (if SnCl 4 is not used as catalyst) and finally the nucleoside synthesis itself-can be combined to a simple one-step/one-pot reaction which generally affords nucleosides in high yields.