Abstract Their ready availability from simple starting materials in only two synthetic steps and their versatility as building blocks for the construction of highly substituted amines and N- heterocycles renders α-(alkylideneamino) nitriles useful synthetic intermediates. Herein, short syntheses of tri-and tetrasubstituted pyrroles including the northern half of the HMG- CoA reductase inhibitor atorvastatin as well as an access to 3-substituted indolizidines will ...
