Organic letters

Synthesis of a cytotoxic ansamycin hybrid

G Jürjens, A Kirschning

文献索引：Mancuso, Lena; Juerjens, Gerrit; Hermane, Jekaterina; Harmrolfs, Kirsten; Eichner, Simone; Fohrer, Joerg; Collisi, Wera; Sasse, Florenz; Kirschning, Andreas Organic Letters, 2013 , vol. 15, # 17 p. 4442 - 4445

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被引用次数: 5

摘要

The synthesis of a new ansamycin macrolactam derivative that contains an ansa chain based on ansamitocin and an aromatic core related to geldanamycin is reported. The selective introduction of the cyclic carbamoyl group at C7 and C9 relies on a