Abstract 1-β-D-Ribofuranosyl-21, 1-(2-deoxy-β-D-erytftro-pentofuranosyl)-27 and 1-β-D- arabinofuranosyl-29 derivatives of 1, 2, 4-triazole-3-sulfonamide (19) have been prepared. Glycosylation of the silylated 19 with 1, 2, 3, 5-tetra-0-acetyl-β-D-ribofuranose (5) in the presence of trimethylsilyl triflate gave the corresponding blocked nucleoside (20), which on ammonolysis afforded 1-β-D-ribofuranosyl-1, 2, 4-triazole-3-sulfonamide (21). ...