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Tetrahedron

Aryl radical cyclisation onto pyrroles

C Escolano, K Jones

文献索引:Escolano, Carmen; Jones, Keith Tetrahedron, 2002 , vol. 58, # 7 p. 1453 - 1464

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被引用次数: 55

摘要

The intramolecular cyclisation of aryl radicals onto a pyrrole is studied. The cyclisation allows the synthesis of either the spiropyrrolidinyloxindole or the pyrrolo [3, 2-c] quinoline skeleton depending on the nature of the protecting group at the N-pyrrole atom. The regiochemistry of the cyclisation is not affected by the substituents on the benzene ring. Some limitations on the utility of tosylmethylisocyanide in pyrrole synthesis are also ...