Polyhedron

Zeolite and sulfated zirconia as catalysts for the synthesis of 5-substituted 1H-tetrazoles via [2+ 3] cycloaddition of nitriles and sodium azide

A Teimouri, AN Chermahini

文献索引：Teimouri, Abbas; Najafi Chermahini, Alireza Polyhedron, 2011 , vol. 30, # 15 p. 2606 - 2610

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被引用次数: 30

摘要

The [2+ 3] cycloaddition between various nitriles and sodium azide proceeds smoothly in the presence of zeolite and sulfated zirconia as effective catalysts, in water and DMF/MeOH, to give the corresponding 5-substituted 1H-tetrazoles in good to high yields. The reaction most probably proceeds through the in situ formation of catalyst azide species, followed by a successive [2+ 3] cycloaddition with the nitriles. This method has the advantages of high ...