() liv: ti~ tl: uid Siiell reportedd that a pyridoxal phos-1) h: it e (l'1> aL4 1) dependent enzyme, alanine racemase from Stt, epiococcus jaecalis, could be inhibited competitively by 4- nitrosalicylaldehyde (2a), presumably because 2a c: ui: idequ: ttely simu1: tte I'd.) To use this ohvrvatioii: ii the basiy for: I general series of simple~ iotihc~ tc~ i~ ocyclic, 1'Pal-specific eiizynie inhibitors, sonie 4-and. j-. ribstituted salicylaldehgdes (2) were syii-tlicwzed arid ...
