Tetrahedron letters

A highly catalytic robust palladium catalyzed cyanation of aryl bromides

PE Maligres, MS Waters, F Fleitz, D Askin

文献索引：Maligres, Peter E.; Waters, Marjorie S.; Fleitz, Fred; Askin, David Tetrahedron Letters, 1999 , vol. 40, # 47 p. 8193 - 8195

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被引用次数: 127

摘要

... K. Takagi, T. Okamoto, Y. Sakakibara, A. Ohno, S. Oka, N. Hayama; Bull. Chem. Soc. Jpn., 49 (1976), pp. 3177–3180. ... TLC and HPLC (Waters Spherisorb S5 OD/CN column) analysis indicated complete consumption of 1 (<0.5%) after 20 h and the mixture was cooled to 80°C. The mixture was gradually diluted with 4:1:4 v/v/v saturated aq. NH 4 Cl-concd NH 4 OH-water solution (33.3 L) over 1 h. The slurry was cooled to -9°C over 1.5 h and filtered. ...