A simple, general distereoselective synthesis of 5-hydroxyalkylbutan-4-olides

CW Jefford, Y Wang

文献索引：Jefford, Charles W.; Wang, Ying Journal of the Chemical Society, Chemical Communications, 1987 , # 20 p. 1513 - 1514

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被引用次数: 8

摘要

5-Hydroxyalkylbutan-4-olides are widespread in Nature and often show biological activity. 1 Consequently, much attention has been paid_to their synthesis2J and exploitation as building blocks for constructing complex natural products .4 In our quest for new, short ways of preparing these entities5 we were surprised that the potential of epoxyalkanoic acids, notwith- standing the widely recognized usefulness of epoxides ,6 had not been exploited for preparing y- ...