The Journal of organic chemistry

Proton-in-Flight Mechanism for the Spontaneous Hydrolysis of N-Methyl O-Phenyl Sulfamate: Implications for the Design of Steroid Sulfatase Inhibitors

DR Edwards, R Wolfenden

文献索引：Journal of Organic Chemistry, , vol. 77, # 9 p. 4450 - 4453

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被引用次数: 5

摘要

... The Journal of Organic Chemistry. ... States. J. Org. Chem. ... conditions. We also present a physical organic description of sulfuryl transfer that should prove useful in predicting the hydrolytic stability of the next generation of sulfatase inhibitors. ...