Investigation of Synthetic Routes to a Key Benzopyran Intermediate of a 5HT4 Agonist

G Rassias, NG Stevenson, NR Curtis…

文献索引：Organic Process Research and Development, , vol. 14, # 1 p. 92 - 98

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被引用次数: 16

摘要

... Organic Process Research & Development. ... GlaxoSmithKline R&D, Chemical Development, Synthetic Chemistry ... Interestingly, only 11% of the combined mass of these reagents ends up as part of the structure in 19, rendering the atom economy of the process extremely poor. ...