The first synthesis of (+)-myxothiazol A 1 was achieved based on a modified Julia olefination between (3, 5R)-dimethoxy-(4R)-methyl-6-oxo-(2E)-hexenamide 3, corresponding to the left side of the final molecule, and 4-(2 ″-benzothiazolyl) sulfonylmethyl-2′-[(1′″R), 6′″- dimethylhepta-(2′″E),(4′″E)-dienyl]-2, 4′-bithiazole 6, corresponding to the right side. The synthesis of (+)-myxothiazol Z 2 was also achieved based on modified Julia ...