Synthetic Communications

A Convenient Methodology for the Selective Reduction of Carboxylic Acids With Benzyltriethyl-Ammonium Borohydride—Chlorotrimethylsilane

J Das, S Chandrasekaran

文献索引：Das, J.; Chandrasekaran, S. Synthetic Communications, 1990 , vol. 20, # 6 p. 907 - 912

全文：HTML全文

被引用次数: 17

摘要

A combination of benzyltriethylammonium borohydride and chlorotrimethylsilane (1:l) in dichloromethane (0-25OC) has been found to be a convenient reagent system for the selective reduction ofcarboxylicacidstoal cohols . ... Recently we reported our results on the facile and ... The mechanism of this reaction and active species ... Unlike borane this reagent system reduces benzoyl ... H3C(CH,),6 COOH 4 H3C (CH2) 16CH20H 97 ... H3C(CH2)3COOH 4 H3C(CH2)3 CH20H 85