Organic reactions on supported reagents recently have received considerable attention from synthetic chemists because of their high efficiency, environmentally benign conditions, and convenient work-up procedure. 1 1. Clark , HJ 1994. Catalysis of Organic Reactions by Supported in Organic Reagents, New York: VCH. ... View all references In particular, silica gel has been shown to be the most useful inorganic solid for effecting a variety of functional group transformation. ...