A convergent synthesis of AR-C123196 utilising reaction between a cyclic carbonate and a phenol for aryl alkyl ether formation

GL Allsop, AJ Cole, ME Giles, E Merifield…

文献索引：Organic Process Research and Development, , vol. 13, # 4 p. 751 - 759

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被引用次数: 11

摘要

... Organic Process Research & Development. ... During development, it became apparent that homocoupling of the boronic acid was occurring as a significant side reaction ... facile Pd(II)-mediated process, in accord with recent literature.(18) Several aspects of the process were fixed ...