Tetrahedron

Synthesis of trisubstituted isoxazoles via in situ trapping strategy from α-nitro carbonyl compounds and methyl ketones or terminal aryl alkenes

Y Yang, M Gao, C Deng, DX Zhang, LM Wu, WM Shu…

文献索引：Yang, Yan; Gao, Meng; Deng, Cong; Zhang, Dong-Xue; Wu, Liu-Ming; Shu, Wen-Ming; Wu, An-Xin Tetrahedron, 2012 , vol. 68, # 31 p. 6257 - 6262

全文：HTML全文

被引用次数: 15

摘要

A highly efficient domino method for the synthesis of trisubstituted isoxazoles has been established from α-nitro carbonyl compounds and methyl ketones or terminal aryl alkenes. Simple and readily available starting materials, mild reaction conditions and very simple operation are significant advantages of the reaction.