Tetrahedron

Synthesis of 4-phosphono-and of 4-(phosphonomethyl)-dl-phenylalanine, two analogues of O-phosphotyrosine

…, N Collignon, A Boumekouez, E de Tinguy-Moreaud…

文献索引：Bayle-Lacoste, Mireille; Moulines, Jean; Collignon, Noel; Boumekouez, Abdelkader; De Tinguy-Moreaud, Eliane; Neuzil, Eugene Tetrahedron, 1990 , vol. 46, # 23 p. 7793 - 7802

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被引用次数: 25

摘要

: 4-Phosphono-DL-phenylalanine 1 was synthetized from 4-bromo-DL-phenylalanine or from 4-(bromomethyl)-bromobenzene; 4-(phosphonomethyl)-DL-phenylalanine 14 was prepared from methyl p-toluate. The interest of these phosphonic analogues arises from their possible interference in the metabolism of O-phosphotyrosine.