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The Journal of Organic Chemistry

Regiospecific electrophilic substitution of aminopyridines: ortho lithiation of 2-, 3-, and 4-(pivaloylamino) pyridines

JA Turner

文献索引:Journal of Organic Chemistry, , vol. 48, # 20 p. 3401 - 3408

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被引用次数: 164

摘要

... Treatment with additional methyl iodide was accompanied by a corresponding decrease in yield of 6e, and, indeed, addition of 3 equiv of methyl iodide resulted in nearly total loss of volatile, organic soluble material, possibly due to quaternization of the ... J. Org. Chem., Vol. ...