A straightforward synthesis of 3, 4-difluoropyrrole

…, VV Smirnov, SG DiMagno

文献索引：Woller, Eric K.; Smirnov, Valeriy V.; DiMagno, Stephen G. Journal of Organic Chemistry, 1998 , vol. 63, # 16 p. 5706 - 5707

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被引用次数: 35

摘要

Halogenated pyrroles have been synthetic targets for over a century. 2, 3, 4, 5- Tetrahalopyrroles were first reported in the 1880s; 1-3 by 1934 Fischer had catalogued more than 60 simple ring-halogenated derivatives in Die Chemie des Pyrrols. 4 The first definitive preparation of an otherwise unsubstituted 3, 4-dihalopyrrole was due to Fischer, who synthesized 3, 4-dichloropyrrole by saponification and double decarboxylation of 3, 4- ...