Pyrimidine-purine and pyrimidine heterodinucleosides synthesis containing a triazole linkage

…, PH Elchinger, PA Faugeras, R Zerrouki

文献索引：Lucas; Elchinger; Faugeras; Zerrouki Nucleosides, Nucleotides and Nucleic Acids, 2010 , vol. 29, # 3 p. 168 - 177

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被引用次数: 8

摘要

This article describes a synthetic route to generate two purine-pyrimidine and pyrimidine heterodinucleosides. Both microwave activated regioselective alkylation using hydride and copper-catalyzed-azide-alkyne-cycloaddition (CuAAC) were used in order to perform the synthesis.