Ligand-promoted C3-selective arylation of pyridines with Pd catalysts: gram-scale synthesis of (±)-preclamol

…, AJF Edmunds, PA Worthington, JA Morris…

文献索引：Ye, Mengchun; Gao, Guo-Lin; Edmunds, Andrew J. F.; Worthington; Morris, James A.; Yu, Jin-Quan Journal of the American Chemical Society, 2011 , vol. 133, # 47 p. 19090 - 19093

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被引用次数: 125

摘要

The first example of Pd-catalyzed, C3-selective arylation of unprotected pyridines has been developed by employing a catalytic system consisting of Pd (OAc) 2 and 1, 10- phenanthroline. This protocol provides an expeditious route to an important class of 3- ...

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