Methylthio activating groups in the synthesis of isoquinolines

MR Euerby, RD Waigh

文献索引：Euerby, Melvin R.; Waigh, Roger D. Journal of the Chemical Society, Chemical Communications, 1984 , # 2 p. 127 - 128

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被引用次数: 2

摘要

Most of the widely used syntheses of isoquinolines proceed by acid-catalysed attack of a suitable functionalised N-substituted phenethylamine or benzylamine on the benzene ring of the amine. They are thus representative of a wider range of reactions proceeding by electrophilic attack on an aromatic system, many of which are dependent on the presence of suitably placed electron-donating substituents. In the absence of activating groups, reactions of the last ...