Resolution of non-protein amino acids via Carica papaya lipase-catalyzed enantioselective transesterification

T Miyazawa, K Onishi, T Murashima, T Yamada…

文献索引：Miyazawa, Toshifumi; Onishi, Kazuki; Murashima, Takashi; Yamada, Takashi; Tsai, Shau-Wei Tetrahedron Asymmetry, 2005 ,  vol. 16,  # 15  p. 2569 - 2573

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被引用次数: 17

摘要

Carica papaya lipase-catalyzed transesterification of the 2, 2, 2-trifluoroethyl esters of N- benzyloxycarbonylated dl-amino acids carrying aliphatic side chains proceeded smoothly and, in almost all the cases, enantiospecifically (E=> 200), affording the l-methyl esters and leaving the d-trifluoroethyl esters intact.