The methyl enol ether of 2-methylcyclohexanone (S)-but-3-en-2-01 to give respectively, the (R)- and ... We considered it likely that a compound of type (1) would undergo the Claisen rearrangement1 stereoselectively, because its two possible chair-like transition states2 differ in that the R' group is quasi-equatorial in one and quasi-axial in the other. The expected products are (2) (major) and (3) (minor), respectively (see Scheme 1). For a synthetic project based on this idea ...
