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Tetrahedron letters

A new reductive acylation of azetidinone disulphide in the route to penems

…, C Scarafile, S Vioglio, E Perrone, G Franceschi

文献索引:Battistini, Carlo; Scarafile, Cosimo; Vioglio, Sergio; Perrone, Ettore; Franceschi, Giovanni Tetrahedron Letters, 1986 ,  vol. 27,  # 4  p. 513 - 516

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被引用次数: 4

摘要

Abstract The use of triethyl phosphite and the appropriate carboxylic anhydridewas found to constitute an efficient method for the conversion of azetidinyl benzthiazolyl disulphides into acylthioazetidinones, allowing a short synthesis of penem FCE 88891 from its penam-1- oxide precursor.