Tetrahedron letters

A palladium-promoted route to 3-alkyl-4-(1-alkynyl)-hexa-1, 5-dyn-3-enes and/or 1, 3-diynes

R Rossi, A Carpita, C Bigelli

文献索引：Rossi, Renzo; Carpita, Adriano; Bigelli, Clara Tetrahedron Letters, 1985 , vol. 26, # 4 p. 523 - 526

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被引用次数: 198

摘要

Abstract Reaction of benzene solutions of arylacetylenes with 1 equiv. of chloroacetone and 2 equiv. of Et 3 N, using a mixture of (PPh 3) 4 Pd and CuJ as catalyst, affords 1, 4-diaryl- butadiynes in very good yields. Under similar reaction conditions aliphatic 1-alkynes yield mixtures of simmetrically disubstituted 1, 4-dialkyl-1, 3-butadiynes and of 3-alkyl-4-(1- alkynyl)-hexa-1, 5-diyn-3-enes.