Efficient synthesis of 3-hydroxy-1, 4-benzodiazepines oxazepam and lorazepam by new acetoxylation reaction of 3-position of 1, 4-benzodiazepine ring

I Cepanec, M Litvic, I Pogorelic

文献索引：Organic Process Research and Development, , vol. 10, # 6 p. 1192 - 1198

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被引用次数: 24

摘要

... Organic Process Research & Development. ... However from the observation of this reaction we concluded that the process presumably includes the iodination of the ... the new syntheses of widely used anxiolytic drugs oxazepam (1) and lorazepam (2). The processes for lorazepam ...