Efficient Synthesis of (S)-2-(Cyclopentyloxycarbonyl)-amino-8-nonenoic Acid: Key Building Block for BILN 2061, an HCV NS3 Protease Inhibitor

X Wang, L Zhang, LL Smith-Keenan…

文献索引：Organic Process Research and Development, , vol. 11, # 1 p. 60 - 63

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被引用次数: 11

摘要

... In summary, we have developed a practical procedure for preparation of (S)-2-( cyclopentyloxycarbonyl)amino ... A recycling process was established for the kinetic resolution to permit more complete conversion ... layer was washed with water (2 × 8.0 L), and the organic solvent ...