Tetrahedron

Microwave-assisted synthesis of the antihyperglycemic drug rosiglitazone

SL Gaonkar, H Shimizu

文献索引：Gaonkar, Santosh L.; Shimizu, Hiroki Tetrahedron, 2010 , vol. 66, # 18 p. 3314 - 3317

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被引用次数: 31

摘要

We developed a simple, rapid, high yielding, and environmentally benign microwave assisted total synthesis of rosiglitazone, an antihyperglycemic agent for diabetes mellitus Type II. We used microwave heating successfully to improve reactions in four of six steps ...