1-(3-Cyanobenzylpiperidin-4-yl)-5-methyl-4-phenyl-1, 3-dihydroimidazol-2-one: A selective high-affinity antagonist for the human dopamine D4 receptor with excellent …

RW Carling, KW Moore, CR Moyes…

文献索引：Journal of Medicinal Chemistry, , vol. 42, # 14 p. 2706 - 2715

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被引用次数: 59

摘要

... Journal of Medicinal ... Departments of Medicinal Chemistry, Biochemistry, and Pharmacology, Merck Sharp and Dohme Research Laboratories, Neuroscience Research Centre ... it is widely accepted that brain dopamine receptors are the primary targets for medical treatment. ...