Inhibitors of hepatitis C virus NS3/4A: α-Ketoamide based macrocyclic inhibitors

S Avolio, K Robertson, JIM Hernando, J DiMuzio…

文献索引：Bioorganic and Medicinal Chemistry Letters, , vol. 19, # 8 p. 2295 - 2298

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被引用次数: 27

摘要

... Bioorganic & Medicinal Chemistry Letters. ... In this Letter, we report our efforts to evaluate the NS3/4A inhibition ability of a hybrid series of molecules designed by the combination of the P2-P4 macrocycle portion of MK-7009 (4, in blue in Fig. ...