Tetrahedron letters

Total synthesis of the marine pyridoacridine alkaloid sebastianine A

L Legentil, J Bastide, E Delfourne

文献索引：Legentil, Laurent; Bastide, Jean; Delfourne, Evelyne Tetrahedron Letters, 2003 , vol. 44, # 12 p. 2473 - 2475

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被引用次数: 22

摘要

The synthesis of the marine alkaloid sebastianine A and of a regioisomer has been accomplished via hetero-Diels–Alder reaction of indole-4, 7-dione or N-tosylindole-4, 7- dione with trifluoroacetamidocinnamaldehyde dimethylhydrazone, and subsequent cyclisation in alkaline conditions.