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Synthesis of benzoxazoles by the copper triflate catalysed reaction of nitriles and o-aminophenols

H Tan, C Pan, Y Xu, H Wang…

文献索引:Tan, Heng; Pan, Cheng-Xue; Xu, Yan-Li; Wang, Heng-Shan; Pan, Ying-Ming Journal of Chemical Research, 2012 , vol. 36, # 6 p. 370 - 373

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被引用次数: 7

摘要

An efficient procedure for the synthesis of benzoxazoles by the heteroannulation of nitriles and o-aminophenols in the presence of a catalytic amount of copper (II) trifluoromethanesulfonate, has been developed. This method represents a practical and attractive alternative for the synthesis of both 2-arylbenzoxazoles and 2-alkylbenzoxazoles.