Synthesis, structures and anti-malaria activity of some gold (I) phosphine complexes containing seleno-and thiosemicarbazonato ligands

A Molter, J Rust, CW Lehmann, G Deepa, P Chiba…

文献索引：Molter, Anja; Rust, Joerg; Lehmann, Christian W.; Deepa, Ganesh; Chiba, Peter; Mohr, Fabian Dalton Transactions, 2011 , vol. 40, # 38 p. 9810 - 9820

全文：HTML全文

被引用次数: 25

摘要

A series of both mono-and dinuclear gold (I) phosphine complexes containing monoanionic seleno-and thiosemicarbazones as ligands were prepared and fully characterized by spectroscopic methods and, in some cases, by single crystal X-ray diffraction. The in vitro anti-malaria activity of some of these compounds was investigated in chloroquine sensitive strains of Plasmodium falciparum. The IC50 results show that the sulfur containing ...