Reaction of Ph3P (SCN) 2 with further orthohydroxy carboxylic acid systems, including substituted β-keto acids: synthesis of novel 2-thio-1, 3-oxazines and their …
KM Pritchard, J Al-Rawi
文献索引：Pritchard, Kaylene M.; Al-Rawi, Jasim Synthetic Communications, 2008 , vol. 38, # 23 p. 4076 - 4096
Abstract We now report the first reaction of Ph3P (SCN) 2 with 4, 6-dihydroxy-5- methylisophthalic acid to give 10-methyl-2, 8-dithio-1, 3-oxazino-1, 3-benzoxazine-4, 6- dione. Also, the enol tautomer has been utilized in the reaction of β-keto acids with Ph3P (SCN) 2 to give novel 2-thio-1, 3-oxazines. Subsequent reaction of the 2-thio-1, 3-oxazines with benzylamine resulted in opening of the oxazine ring and gave novel dibenzylamino- ...
