前往化源商城

Pyranoxanthones: Synthesis, growth inhibitory activity on human tumor cell lines and determination of their lipophilicity in two membrane models

…, MH Vasconcelos, M Pedro, J Barbosa, L Gales…

文献索引:Azevedo, Carlos M.G.; Afonso, Carlos M.M.; Soares, Jose X.; Reis, Salette; Sousa, Diana; Lima, Raquel T.; Vasconcelos, M. Helena; Pedro, Madalena; Barbosa, Joao; Gales, Luis; Pinto, Madalena M.M. European Journal of Medicinal Chemistry, 2013 , vol. 69, p. 798 - 816

全文:HTML全文

被引用次数: 7

摘要

Abstract The benzopyran and dihydrobenzopyran moieties can be considered as “privileged motifs” in drug discovery being good platforms for the search of new bioactive compounds. These moieties are commonly found fused to the xanthonic scaffold belonging to the biologically important family of the generally designated prenylated xanthones. Several pyranoxanthones have shown promising antitumor activity and since most of them are ...