… efficient synthesis of [18F] fluoronicotinamides,[18F] fluoroisonicotinamides and [18F] fluorobenzamides as potential pet radiopharmaceuticals for melanoma imaging

I Al Jammaz, B Al??Otaibi, S Okarvi…

文献索引：Al Jammaz; Al-Otaibi; Okarvi; Amartey Journal of Labelled Compounds and Radiopharmaceuticals, 2011 , vol. 54, # 6 p. 312 - 317

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被引用次数: 3

摘要

Abstract In an attempt to simplify nucleophilic radiofluorination reactions to be amenable for automation, a series of [18 F] fluoronicotinamides,[18 F] fluoroisonicotinamides and [18 F] fluorobenzamides were synthesized using one-step synthetic approach involving displacement reactions on trimethylammonium-nicotinamide, trimethylammonium- isonicotinamide and trimethylammonium-benzamide precursors. Based on starting [18 F]- ...